Faculty

The CR-PSOC is uniquely well positioned to support this mission through its diverse team of 12 physical scientists and 8 cancer researchers from fields encompassing physics, chemistry, biomedical engineering, biophysics, biochemistry, pharmacology, and hematology-oncology.  The proposed Center will be led by a pair of Northwestern researchers: renowned physical scientist, Thomas O’Halloran in the role of Contact Principal Investigator, and internationally recognized cancer researcher, Jonathan D. Licht, MD, complementing him in a multi-leadership model in the role of PD/PI.  They will be supported by a team of researchers from the Chicago region’s premier research institutions: Northwestern University (NU), the University of Chicago (UoC) and University of Illinois at Chicago (UIC).  The Center’s project leaders recruited additional thought leaders in the physical sciences and chromatin fields from outside Chicago, namely  MIT, Memorial-Sloan Kettering Cancer Center, and the University of Massachusetts Medical School.

UNIT PROJECT TITLE PROJECT TEAM* DEPARTMENTAL AFFILIATION INSTITUTION
Administrative Core Contact PI Thomas O’Halloran Chemistry Northwestern
PI/PD Jonathan Licht Hematology & Oncology University of Florida
Center Administrator Sheila Judge Chemistry of Life Processes Institute Northwestern
Patient Advocate Stuart Cornew

Project 1

 

Chemical Biology Approaches

Ionic modulation of chromatin in cancer Thomas  O’Halloran Chemistry Northwestern
Andrew Mazar Molecular Bioscience Northwestern
Vadim Backman Biomedical Engineering Northwestern
Igal Szleifer Biomedical Engineering Northwestern
Jack Kaplan Biochemistry and Molecular Genetics Univ. of Illinois-Chicago
Ming Zhao Medicine Northwestern
John Marko Molecular Biosci./Physics Northwestern
Navdeep Chandel Medicine Northwestern

Project 2

 

Genetic Approaches

Molecular modulation of chromatin and nuclear structure in cancer Jonathan Licht Hematology & Oncology University of Florida
Chuan He Chemistry Univ. of Chicago
Ross Levine Medicine MSKCC
Job Dekker Biochemistry/ Mol. Pharmacol. Univ. Mass. Med. School
Lucy A. Godley Medicine Univ. of Chicago

Project 3

 

Biophysical Approaches

Mechanics of nuclei, chromosomes and chromatin in cancer John Marko Molecular Bioscience/ Physics & Astronomy Northwestern
John Crispino Medicine/Heme-Onc Northwestern
Leonid Mirny Health Sciences Technology/ Physics MIT
Robert Goldman Cell and Molecular Biology Northwestern
Vadim Backman Biomedical Engineering Northwestern
Igal Szleifer Biomedical Engineering Northwestern
Adilson Motter Physics & Astronomy Northwestern
Cores PDX Tumor Core Teresa Woodruff Obstetrics and Gynecology Northwestern
Nanocytometry Core Vadim Backman Biomedical Engineering Northwestern
Education & Outreach Unit Sheila Judge Chemistry of Life Processes Institute Northwestern
Benette Phillips Lurie Cancer Center Northwestern